Check out the main picture from the Wikipedia article on Asperger's syndrome. Note the odd behavior of the boy, who as Wikipedia says, is obsessed with molecular structure (bonus points for identifying the molecule without cheating and visiting the Wikipedia page).
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| Caption: "People with Asperger syndrome often display intense interests, such as this boy's fascination with molecular structure." Source: Wikipedia. |
This immediately suggests an opportunity for total synthesis groups to get grants: just repurpose the synthesis and NMR studies as a therapeutic exercise for the PI with Asperger's disorder. No FDA approval or expensive clinical studies required.
There are (obviously) some changes going into place, which psychologists find important and you can read about if you like. The changes (and the manual itself) are not without controversy. Most prominently praised/criticized have been the elimination of two items: dyslexia and Asperger's syndrome. That's interesting, as it's my understanding that both are relatively common and I know people who self-identify with either disorder. I can't help but wonder how these things impact treatments and outcomes of individuals.

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